Download e-book for iPad: Drug Design: Medicinal Chemistry: A Series of Monographs, by E. J. Ariëns

By E. J. Ariëns

ISBN-10: 0120603055

ISBN-13: 9780120603053

Drug layout, quantity V covers the elemental methods to the improvement of bioactive compounds. The e-book discusses the usage of operational schemes for analog synthesis in drug layout; the layout of enzyme inhibitors (transition nation analogs); and the importance of structure-absorption-distribution relationships for drug layout.
The textual content describes the function of charge-transfer methods within the motion of bioactive fabrics, in addition to the methods to the rational blend of antimetabolites for melanoma chemotherapy. The physicochemical, quantum chemical, and different theoretical thoughts for the knowledge of the mechanism of motion of significant anxious approach (CNS) brokers, akin to psychoactive medicines, narcotics, and narcotic antagonists and anesthetics, also are encompassed.
Chemists, biochemists, pharmacologists, and other people eager about drug layout will locate the ebook invaluable.

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Drug Design: Medicinal Chemistry: A Series of Monographs, Vol. 5 by E. J. Ariëns

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