Pharmacokinetics and Metabolism in Drug Design, Volume 51 - download pdf or read online

By Dennis A. Smith,Charlotte Allerton,Amit S. Kalgutkar,Han van de Waterbeemd,Don K. Walker

ISBN-10: 3527329544

ISBN-13: 9783527329540

during this re-creation of a bestseller, the entire contents were introduced upto-date through addressing present criteria and most sensible practices within the review and prediction of ADMET houses. even if the former bankruptcy format has been retained, sizeable revisions were made, with new subject matters corresponding to pro-drugs, lively metabolites and transporters coated intimately in a fashion beneficial to the Drug Discovery scientist. The authors talk about the parameters and strategies very important for the absorption, distribution and retention of drug compounds within the physique, plus the capability difficulties created through their transformation into poisonous byproducts.

whereas aimed toward all these dealing professionally with the improvement and alertness of pharmaceutical components, the easily understandable kind makes this ebook both compatible for college students of pharmacy and comparable matters. Uniquely accomplished, the publication relates physicochemistry and chemical constitution to pharmacokinetic homes and finally drug efficacy and safety.

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Pharmacokinetics and Metabolism in Drug Design, Volume 51 (Methods and Principles in Medicinal Chemistry) by Dennis A. Smith,Charlotte Allerton,Amit S. Kalgutkar,Han van de Waterbeemd,Don K. Walker


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